How Important is Nitric Oxide to Muscle Growth?

‘Been struggling to build muscle? If so, one factor that you should start paying attention to is your nitric oxide (NO) levels. For those who are not familiar with NO, this is a good article to become familiar with the compound. For athletes and fitness fans who are acquainted with this chemical, read on to find out ways to boost NO levels for maximum muscle growth and maximum athletic performance.

 

What is Nitric Oxide?

Nitric oxide is a substance generated by the endothelium, the lining of blood vessels. It relaxes the muscles that surround the interior of arteries, allowing them to expand and improve blood flow.

Because the endothelium is sensitive to chemical and physical variables in our blood vessels, it boosts the synthesis of nitric oxide when it detects a need for more blood flow due to situations such as physical exercise or emotional excitement.  

 

The Major Benefits of Nitric Oxide

Having high levels of nitric oxide can improve blood vessel health, increase lean muscle mass, reduce inflammation, and lower blood pressure since it expands arteries and veins throughout the body. 

The best part of this is that it also significantly lowers your risk of heart disease at the same time- as an added health benefit. Nitric Oxide helps to protect against cardiovascular disease by hindering arterial degeneration caused by aging, and aiding in heart repair after myocardial injury. 

How so? Well, the heart needs to pump the blood around the body, with the help of nitric oxide, the blood vessels relax and allow for sufficient blood flow. This helps the heart work more efficiently because less pressure is placed on it. By increasing nitric oxide levels, it allows for more oxygen and nutrients to be carried around the body without exhausting the heart.

 

Nitric Oxide Effects on Muscle Growth

Nitric oxide is a potent vasodilator and has been discovered to be a very important contributor in increasing muscle mass. This molecule helps you build muscle by jump starting your body's natural protein building process.

Titled as a "miracle molecule" by scientists, it helps your muscles grow bigger, faster and stronger compared to other muscle building supplements available on the market. Nitric oxide is essential to the blood flow that delivers oxygen and nutrients to muscles; the more oxygen you have circulating, the longer your endurance will be and the faster your recovery will be. With both factors being super important in building muscle.

 

HUGE Muscle Pumps.


When you lift weights, your muscles contract generating nitric oxide. NO improves mechanical and metabolic muscle power through the c-GMP mediated pathway.   Because nitric oxide is a potent vasodilator, it  relaxes the smooth muscles of the blood vessels in your muscles, enabling increased blood flow. This will cause your veins to swell and your muscles to protrude. A good muscle pump allows you to see the results of your hard work, which motivates you to work even harder and feel full. We all know what Arnold said about what “The Pump” feels like. If you don’t know, treat yourself to highly inspiring 1977 Documentary - “Pumping Iron”  

https://pubmed.ncbi.nlm.nih.gov/10442090/


Boosts Endurance.



During strenuous activity, your body breaks down carbohydrates, glycogen, and other molecules to produce adenosine triphosphate, or ATP, which is subsequently transformed into energy.


However, this process consumes a lot of oxygen and produces hydrogen ions, which accumulate in your muscles, producing a decrease in pH and interfering with muscular contraction. This is what produces the mid-workout burn that makes you want to quit. To counteract this, nitric oxide maintains regular blood flow to the muscles to supply oxygen and nutrients, allowing you to workout harder and for longer periods of time without becoming fatigued.

https://pubmed.ncbi.nlm.nih.gov/1842855/ 

 

Decrease Soreness and Faster Recovery.


Weight-training sessions are so strenuous that the body is unable to deliver adequate oxygen to sustain energy. Lactic acid accumulates in the muscles, producing exhaustion, excessive fatigue, physical weakness, muscular cramps, and discomfort. Nitric oxide avoids this by boosting blood flow to the muscles, which ensures that your body has adequate oxygen to generate power.

Following an intense, focused gym session, nitric oxide ensures that your muscles are filled with nutrition and oxygen, and that any lactic acid accumulation is removed. This reduces the amount of time you need to recover before your next training session.

https://pubmed.ncbi.nlm.nih.gov/34013839/

 

Supplements that Boost Nitric Oxide levels

NO gets depleted during workout sessions and this is why it’s very important to include nitric oxide boosting supplements before and after training to maintain optimum blood flow. While there are different ways to boost nitric oxide levels, the best and most effective route is through strategic supplementation.

 
L-citrulline


There are many supplements that increase nitric oxide to help fuel muscle mass gains, but only a few work well. Studies show that L-citrulline can boost nitric oxide levels effectively resulting in improved O2 uptake kinetics and greater exercise performance in human subjects.

https://pubmed.ncbi.nlm.nih.gov/26023227/ 

 

Human Growth Hormone


HGH therapy
has been shown to increase nitric oxide production in both growth hormone-deficient patients and healthy individuals. What happens is that HGH stimulates the release of insulin-like growth factor-1 (IGF-1), that interacts with muscle fibers to produce NO which in turn aids in muscle tissue growth. This is the reason why HGH injections gained a fast popularity among athletes, body builders, and fitness buffs because only a small amount of HGH dosing is required to produce significant results in your muscle building regimen in an insanely short amount of time, and I mean within a few weeks! For the best HGH supplement for men and women, choose a bioidentical 141 amino acid sequence formula using r-DNA technology such as Biotropin® HGH. 

The typical HGH dosage for effective muscle building for most men can self-administer around 4 to 6 IU per day while women can take 1 to 3 IU per day as the most common starting dose.

https://elitebioscience.co/collections 

https://pubmed.ncbi.nlm.nih.gov/8981915/ 


Cardarine GW-0742.


Cardarine is a Peroxisome proliferator-activated receptor or PPAR activator, and was initially researched for its fat-burning potential and further developed to potentially treat health issues around the heart and blood vessels. Cardio Shred® is the best Cardarine (GW0742) in the market, and is known to have a range of benefits for athletic performance and muscle building, including reduction of inflammation and an increase in fat-burning potential. Research suggests that Cardarine (GW0742) can be effectively dosed at 12.5mg - 25mg per day.

As a PPAR-delta agonist, Cardio Shred® (Cardarine) increases fat burning and energy metabolism to nourish muscle fibers that significantly contributes to lean mass gains. Cardio Shred® also maintains quality blood flow by increasing nitric oxide production, minimising oxidative damage to the blood vessels that supply oxygen and protein-building amino acids for muscle growth. Cardio Shred® is also studied to suppress inflammation (another benefit of activating the PPAR-delta pathway) thus lowering the risk of cardiovascular diseases.

Long story short, Nitric Oxide is a powerful muscle building molecule with infinite health benefits. And we have just presented some key biohacking compounds that can help increase your NO production over the long and short-term leading to a grander physique and better health. Now it’s over to you to access these tools and get to work in the gym.

In good health, the Elite Sarms Team. 🙏🏼 

 

https://www.elitesarms.com/products/cardarine-gw0742

https://www.frontiersin.org/articles/10.3389/fimmu.2021.783780/full 

https://www.sciencedirect.com/science/article/abs/pii/S0027510705002575 

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