Hormones and How they Affect Body Fat Loss

Hormones are biochemical messengers secreted by endocrine glands to control the different processes in your body, especially your metabolic pathways. If you are having difficulty losing weight or simply looking to shed fat, understanding your hormones and working with them can help you take your fat loss to the next level.

In this article, we will review the major hormones that affect the accumulation of adipose tissue and the metabolism of fat, which are vital to your body transformation journey. By improving the efficacy of your hormone profile, homeostasis is reached, leading to better fat loss. Read on for understanding of how this works.

Leptin and Leptin Resistance 

Synthesized by fat cells, the hormone leptin is secreted into the bloodstream to reduce a person’s appetite and control how the body stores adipose tissues. This means that if you have a higher body fat percentage, your leptin levels are higher. You get to think, okay, if I have a higher amount of leptin, that means lesser cravings because it is an appetite suppressant. 

The problem is with higher amounts of this hormone, its sensitivity is also greatly reduced. As a result, you don’t feel full during and after a meal... Which eventually leads to over-eating and weight gain. 

Solution: Regular physical exercise, sufficient sleep, a decrease in sugar consumption are helpful steps you can adopt to improve leptin sensitivity.


Insulin Regulates Fat metabolism

Insulin holds a major role in regulating carbohydrates and fat metabolism. Where lipid metabolism is concerned, insulin decreases the rate of lipolysis in adipose tissue while stimulating fatty acid synthesis and uptake of triglycerides from the blood, leading to fat accumulation.

Insulin resistance is very rampant today due to hereditary predisposition, stressful lifestyles, diet, and environmental factors. This leads to hyperinsulinemia because your body doesn’t respond to the effects of insulin. This eventually results in the abnormal accumulation of fat tissues in the body and the development of metabolic disorders.

Solution: GW0742, a selective peroxisome proliferator-activated receptor (PPAR)-δ agonist, has been shown to improve metabolic abnormalities including Insulin Resistance in skeletal muscle of lab mice. 1ml a day of Elite Sarms Cardio Shred® Cardarine (GW0742) maximizes your body’s fat burning capacity as it increases glucose uptake to fuel up your muscles and stimulate lean mass gains.

https://pubmed.ncbi.nlm.nih.gov/21864752/ 

https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/expert-answers/hyperinsulinemia/faq-20058488 

https://www.elitesarms.com/products/cardarine-gw0742 

https://pubmed.ncbi.nlm.nih.gov/26508837/ 


Human Growth Hormone (HGH) Speeds up Lipolysis

Human Growth Hormone (HGH) also called Somatotropin, is anabolic, particularly for your bones and muscles. What’s unique about HGH is that it has an opposite effect on fats, by stimulating the breakdown and oxidation of adipocytes. 

The most immediate effect of growth hormone (GH) administration in humans is a significant increase in free fatty acids after 1-2 hours, reflecting the stimulation of lipolysis and ketogenesis. The insulin-antagonistic effects of GH help in shredding fat stores in the body while simultaneously building lean muscle and bone density.

Solution: Optimize your HGH levels to easily burn excess fat, including those stubborn lumps that cling to your body despite your regular workouts. Biotropin® HGH stimulates lipolysis, a process for burning adipose tissues, thus promoting weight loss. Biotropin® HGH also stimulates hormone-sensitive lipase (HSL) enzyme to facilitate fat cell breakdown by releasing it from adipose tissues, resulting in a significant reduction of body fat.

https://pubmed.ncbi.nlm.nih.gov/12914720/

https://pubmed.ncbi.nlm.nih.gov/1861630/ 


Androgens Decreases Fat Buildup

Androgens have a negative effect on adipogenesis and lipid synthesis by up-regulating the Androgen Receptors for catecholamine, thus increasing lipolysis. In addition, androgens reduce lipoprotein lipase (LPL) activity that is necessary for fat accumulation. By inhibiting the LPL enzyme, it also stops adipose tissue from building up on skeletal muscles and organs.

Solution: LGD4033 (Physique 400®) is one of the best SARMs for muscle-building and fat loss. Thanks to its potency that equals androgenic hormones like Testosterone and DH, Physique 400® increases fat loss while growing lean muscles, affecting no other organs because of the high selectivity of its effects mainly confined to your bones, skeletal muscles and connective tissues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770848/

https://www.elitesarms.com/collections/individual-sarms/products/physique-400-lgd4033 

 

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