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By: M.G. Thibault Edited by Ryan McTeigue


Aging leads to a series of changes in an organism as deep as the cellular level. Although, the mechanisms that underlie aging are poorly understood, innovations in science continue to identify factors that explain the decline in fitness and the rise of different health problems that go with advancing age. 

While slowing the aging process remains to be a popular topic, what’s even more compelling is the subject of Age-reversal; this is referred to as Rejuvenation. 

Rejuvenation is a process that not only defers aging, but literally reverts it- resulting in a younger cell, tissue, or body. Rejuvenation includes diminishing all the damages your body has accumulated throughout its lifespan, and erasing the hallmarks of a matured age. Come to think of it, successful rejuvenation not only leads to the extension of life but ultimately to eternal youth! Does it look like something you’d be interested in? Read on…

https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.13483 

 

Cell-regenerating Nutrition

Our body is an extraordinary machine and its primary fuel are the nutrients we get from the food we eat on a daily basis. By purposefully consuming foods that have ‘supercharging compounds’, a person can promote the rapid regeneration and restoration of some of the body’s most important  tissues and organs.

Nerve-regenerative substances: 
A 2010 study published in the journal Rejuvenation Research, for instance, found a combination of blueberry, green tea and carnosine have neuritogenic (i.e. promoting neuronal regeneration) and stem-cell regenerative effects in an animal model of neurodegenerative disease. Other researched neuritogenic substances include: curcumin, Lion’s Mane Mushroom, and apigenin, a plant flavonoid usually found in celery.

On the other hand, you can stimulate liver mass regeneration and function by ingesting via supplements that focus on liver renewal such as Korean Ginseng,  Rooibos, Vitamin E, and  Carvacrol, a compound  found in oregano.

https://pubmed.ncbi.nlm.nih.gov/20586644/ 

http://www.thehealersjournal.com/2014/09/25/how-to-regenerate-your-bodys-cells-with-food-and-herbs/ 

https://pubmed.ncbi.nlm.nih.gov/24266378/ 

https://pubmed.ncbi.nlm.nih.gov/30949912/ 

 

Age-defying Exercises

According to a medical article, exercise improves muscle health by renewing the powerhouse of the cells: the mitochondria. Mitochondria are vital to the proper functioning of our bodies, and the improvement of our overall health and longevity.

Aerobic exercise, in particular, positively affects the mitochondria through a process called “mitophagy.” Mitophagy is a mechanism by which damaged or defective mitochondria are selected and removed, usually after a period of stress. This keeps skeletal muscle healthy and strong by improving the mitochondrial quality of the muscle fibers.

If you are a gym person- the treadmill, elliptical or rowing machine may be your go to equipment to achieve your fill of cardio exercises. Likewise, if you prefer the outdoors, you may try swimming, soccer, triathlons and cross country skiing as enjoyable alternatives to improve your aerobic capacity.

https://www.medicalnewstoday.com/articles/319532#Exercise-promotes-mitophagy-in-mice

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630798/ 

 

Supplements for Age-Reversal

In the ever-evolving world of Cellular rejuvenation, supplements are constantly being discovered and re-formulated. So far, the following are considered to be on top of the food chain when it comes to reverting the aging process:

There are secretagogues, which stimulates the endocrine glands’ ability to secrete more Growth Hormone, which in turn affects the major metabolic pathways in the body, such as fat oxidation, glucose utilization, muscle synthesis, and collagen production just to name a few.

Rejuvenation procedures in private clinics almost always integrate bio-identical Somatropin injections as part of their hormone optimization courses, while others employ drips and infusions of high doses of Vitamin C to regenerate hormones that have degraded. A powerful electron donor, vitamin C has the capacity to provide electrons in order to resurrect the form and function of estradiol, progesterone, and testosterone.

https://www.elitesarms.com/collections/anti-aging/products/gh-pep-mk677 

https://www.healthline.com/health/vitamin-c-injection



Current Modalities on Rejuvenation

 

Ablative laser resurfacing is generally considered to be the gold standard for the rejuvenation of facial photo-damage and scarring. The procedure is a wounding laser that gets rid of the thin outer layer of skin (epidermis) and heats the underlying skin (dermis), which then triggers the growth of new collagen fibers. As the epidermis heals and regrows, the treated area appears smoother and tighter.

 

 

 

 

 

Neck rejuvenation mainly targets skin laxity, that often increase with age due to progressive loss of bone mass, increased subcutaneous fat, and loosening of the connective tissue framework. Using unipolar and bipolar radiofrequency or Infra-red light, sagging skin in the neck area is targeted yielding a tighter, firmer, and younger looking skin just after a few sessions.

A new paradigm for human cell rejuvenation, cellular reprogramming proves to be a promising route when it comes to retracting the procession of aging, which is the basis of rejuvenation. 

This is the most recent breakthrough in the anti-aging field, which involves a genetic or chemical method to reverse the epigenetic age of cells. This genetic code instructs mature, specialized cells to read the right genes at the right time, as though they were young again. The factors scientists are currently using to reprogram these mature cells are called Yamanaka factors, which can turn back an adult cell into a young, pluripotent stem cell. Literally!


https://www.mayoclinic.org/tests-procedures/laser-resurfacing/about/pac-20385114

https://www.researchgate.net/publication/225927112_Treatment_of_Neck_Laxity_with_Radiofrequency_and_Infrared_Light 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960911/